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If you’ve ever done everything “right” – cut the calories, walked your 10,000 steps, swapped wine for water – and still watched the scale refuse to move, you’ll want to keep reading.
Contrary to what most believe, it’s not a willpower problem – It’s biology.
Hormones change, metabolism slows, and the belly fat that wasn’t there five years ago is suddenly permanent.
That’s why we looked at GLP-1 supplements.
Rooted in award-winning GLP-1 science, these supplements aim to stimulate your natural GLP-1 hormone response, reducing hunger, cravings, and making weight loss easier.1
The challenge is choosing the right one.
So, we tested two top GLP-1 booster formulas: ColonBroom GLP-1 Booster and Happy Mammoth Ultimate GLP-1™.
The only question is which one is #1?
Most people think weight gain is about age, and there’s nothing they can do about it.
But age is only part of the story; at the center of it is GLP-1.
GLP-1 tells your brain you’re full, slows digestion, curbs cravings, and keeps blood sugar stable.
However, as we age, GLP-1 levels start declining, potentially contributing to metabolic dysfunction and chronic low-grade inflammation. 2
This doesn’t just drive weight gain — especially around the belly — it drains your energy too.
While GLP-1 injectables exist, they come with a steep price tag and a long list of side effects most people aren’t prepared for.
That’s why many turn to natural GLP-1 boosters, and when the right ingredients are combined, they can support GLP-1 and:
The real challenge? Finding a GLP-1 supplement that actually delivers.
So we did the work. We put ColonBroom GLP-1 Booster and Happy Mammoth Ultimate GLP-1 head to head, and what we found even surprised us.

ColonBroom comes in strong with clinically studied ingredients that target the root cause of weight gain.
Its formula targets GLP-1 activation, blood sugar, inflammation, and insulin sensitivity all at once.
Berberine (200mg) is the engine, with solid clinical backing for GLP-1 activation. 4
Quercetin handles inflammation while zinc supports insulin signaling. 5,6
Finally, polygonum cuspidatum adds cardiovascular and antioxidant protection.
Happy Mammoth keeps it simpler.
Eriomin® stimulates GLP-1 production, Morosil® targets fat loss, Supresa® saffron curbs cravings and snacking. 7
Berberine rounds it out, targeting GLP-1.
The ingredients are high-quality and proprietary, but none of the dosages are disclosed.
That’s the main drawback of this product, as it makes it impossible to know whether you’re getting enough of any ingredient to actually move the needle.

While both of these products offer superb GLP-1 support (probably the best in the market), there are two crucial things to keep in mind:
Happy Mammoth targets GLP-1 stimulation and appetite suppression, and ColonBroom goes further to include inflammation, blood sugar, as well as cardiovascular and antioxidant support.
Happy Mammoth uses proprietary ingredients but doesn’t disclose their doses. Meanwhile, ColonBroom’s ingredients are crystal clear.
Our editorial team recruited 12 women between the ages of 30 and 60 to test both supplements for a month.
Six onHappy Mammoth and six on ColonBroom.
They all received the same instructions: take it daily, don’t change anything else, report back honestly.
Less snacking, reduced appetite, and some bloating relief.
But by week four, most felt the effect had plateaued.
Appetite was somewhat better, but weight hadn’t moved much.
Most reported steadier energy, fewer cravings, and less bloating by week two.
By week four, clothes were fitting much better without anything else changing.
In the end, all six women decided to continue ColonBroom while only two stuck with Happy Mammoth.

These two products are definitely industry leaders.
Both of them:
If craving control is all you need, Happy Mammoth will do the job.
But if you’ve been dealing with stubborn weight, energy crashes, or cravings that just won’t quit – that’s not an appetite problem.
That’s a metabolic problem, and ColonBroom is built for exactly that, targeting blood sugar, inflammation, and GLP-1 activation all at once, so your body finally has what it needs to actually change.
7 sources
GLP-1-based therapy for obesity – Lasker Foundation
https://laskerfoundation.org/winners/glp-1-based-therapy-for-obesity/
Hallmarks of Aging and How GLP-1 Medications Address Them | AgelessRx
https://agelessrx.com/hallmarks-of-aging-and-how-glp-1-medications-address-them/
Tips for activating your GLP-1 levels naturally | Ohio State Health & Discovery
https://health.osu.edu/wellness/exercise-and-nutrition/activiating-glp-1-naturally
Berberine induces GLP-1 secretion through activation of bitter taste receptor pathways – PubMed
Association of inflammation biomarkers with food cravings and appetite changes across the menstrual cycle – ScienceDirect
https://www.sciencedirect.com/science/article/abs/pii/S2405457723001468
Resveratrol in cardiovascular disease: what is known from current research? – PubMed
Ultimate GLP-1: Increase Natural GLP-1 Levels & Reduce Appetite
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